Journal Articles | Book Sections | Preprints | Conference Proceedings
Magazine Articles | Thesis | Metrics et cetera


Journal Articles

Ambra1 spatially regulates Src activity and Src/FAK-mediated cancer cell invasion via trafficking networks
C Schoenherr, A Byron, E Sandilands, K Paliashvili, GS Baillie, A García-Muñoz, C Valacca, F Cecconi, B Serrels, MC Frame
eLife 6, e23172 (2017)
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Ligand-induced epitope masking: Dissociation of integrin α5β1-fibronectin complexes only by monoclonal antibodies with an allosteric mode of action
AP Mould, JA Askari, A Byron, Y Takada, TA Jowitt, MJ Humphries
Journal of Biological Chemistry 291, 20993–21007 (2016)
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Adhesion protein networks reveal functions proximal and distal to cell-matrix contacts
A Byron, MC Frame
Current Opinion in Cell Biology 39, 93–100 (2016)
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Identification of novel pathways linking epithelial-to-mesenchymal transition with resistance to HER2-targeted therapy
H Creedon, L Gómez-Cuadrado, Ž Tarnauskaitė, J Balla, M Canel, KG MacLeod, B Serrels, C Fraser, A Unciti-Broceta, N Tracey, T Le Bihan, T Klinowska, AH Sims, A Byron, VG Brunton
Oncotarget 7, 11539–11552 (2016)
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Proteomic analysis of integrin-associated complexes from mesenchymal stem cells
JN Ajeian*, ER Horton*, P Astudillo*, A Byron, JA Askari, A Millon-Frémillon, D Knight, SJ Kimber, MJ Humphries, JD Humphries
Proteomics Clinical Applications 10, 51–57 (2016)
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Genetic background is a key determinant of glomerular extracellular matrix composition and organization
MJ Randles, AS Woolf, JL Huang, A Byron, JD Humphries, KL Price, M Kolatsi-Joannou, S Collinson, T Denny, D Knight, A Mironov, T Starborg, R Korstanje, MJ Humphries, DA Long, R Lennon
Journal of the American Society of Nephrology 26, 3021–3034 (2015)
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Definition of a consensus integrin adhesome and its dynamics during adhesion complex assembly and disassembly
ER Horton*, A Byron*, JA Askari, DHJ Ng, A Millon-Frémillon, J Robertson, EJ Koper, NR Paul, S Warwood, D Knight, JD Humphries, MJ Humphries
Nature Cell Biology 17, 1577–1587 (2015)
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Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity
A Serrels*, T Lund*, B Serrels**, A Byron**, RC McPherson, A von Kriegsheim, L Gómez-Cuadrado, M Canel, M Muir, JE Ring, E Maniati, AH Sims, JA Pachter, VG Brunton, N Gilbert, SM Anderton, RJB Nibbs, MC Frame
Cell 163, 160–173 (2015)
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Defining the phospho-adhesome through the phosphoproteomic analysis of integrin signalling
J Robertson, G Jacquemet, A Byron, MC Jones, S Warwood, JN Selley, D Knight, JD Humphries, MJ Humphries
Nature Communications 6, 6265 (2015)
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A proteomic approach reveals integrin activation state-dependent control of microtubule cortical targeting
A Byron*, JA Askari*, JD Humphries*, G Jacquemet, EJ Koper, S Warwood, CK Choi, MJ Stroud, CS Chen, D Knight, MJ Humphries
Nature Communications 6, 6135 (2015)
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Microtubule-dependent modulation of adhesion complex composition
DHJ Ng, JD Humphries, A Byron, A Millon-Frémillon, MJ Humphries
PLoS ONE 9, e115213 (2014)
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Exploring mechanisms of acquired resistance to HER2 (human epidermal growth factor receptor 2)-targeted therapies in breast cancer
H Creedon, A Byron, J Main, L Hayward, T Klinowska, VG Brunton
Biochemical Society Transactions 42, 822–830 (2014)
PubMed | Blog

Glomerular cell crosstalk influences composition and assembly of extracellular matrix
A Byron*, MJ Randles*, JD Humphries, A Mironov, H Hamidi, S Harris, PW Mathieson, MA Saleem, SS Satchell, R Zent, MJ Humphries, R Lennon
Journal of the American Society of Nephrology 25, 953–966 (2014)
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Global analysis reveals the complexity of the human glomerular extracellular matrix
R Lennon, A Byron, JD Humphries, MJ Randles, A Carisey, S Murphy, D Knight, PE Brenchley, R Zent, MJ Humphries
Journal of the American Society of Nephrology 25, 939–951 (2014)
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Rac1 is deactivated at integrin activation sites through an IQGAP1–filamin-A–RacGAP1 pathway
G Jacquemet, MR Morgan, A Byron, JD Humphries, CK Choi, CS Chen, PT Caswell, MJ Humphries
Journal of Cell Science 126, 4121–4135 (2013)
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The effect of peptide adsorption on signal linearity and a simple approach to improve reliability of quantification
S Warwood*, A Byron*, MJ Humphries, D Knight
Journal of Proteomics 85, 160–164 (2013)
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Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance
D Soteriou*, B Iskender*, A Byron*, JD Humphries, S Borg-Bartolo, M-C Haddock, MA Baxter, D Knight, MJ Humphries, SJ Kimber
Journal of Biological Chemistry 288, 18716–18731 (2013)
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Defining the extracellular matrix using proteomics
A Byron, JD Humphries, MJ Humphries
International Journal of Experimental Pathology 94, 75–92 (2013)
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Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver
ST Rashid*, JD Humphries*, A Byron, A Dhar, JA Askari, JN Selley, D Knight, RD Goldin, M Thursz, MJ Humphries
Journal of Proteome Research 11, 4052–4064 (2012)
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Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment
A Byron, JD Humphries, SE Craig, D Knight, MJ Humphries
Proteomics 12, 2107–2114 (2012)
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Alternative cellular roles for proteins identified using proteomics
A Byron, JD Humphries, MJ Humphries
Journal of Proteomics 75, 4184–4185 (2012)
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A syndecan-4 hair trigger initiates wound healing through caveolin- and RhoG-regulated integrin endocytosis
MD Bass, RC Williamson, RD Nunan, JD Humphries, A Byron, MR Morgan, P Martin, MJ Humphries
Developmental Cell 21, 681–693 (2011)
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Analyzing the anatomy of integrin adhesions
A Byron
Science Signaling 4, jc3 (2011)
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Proteomic analysis of integrin adhesion complexes
A Byron, JD Humphries, MD Bass, D Knight, MJ Humphries
Science Signaling 4, pt2 (2011)
PubMed | Slideshow | Blog

Adhesion signalling complexes
A Byron*, MR Morgan*, MJ Humphries
Current Biology 20, R1063–R1067 (2010)
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Anti-integrin monoclonal antibodies
A Byron, JD Humphries, JA Askari, SE Craig, AP Mould, MJ Humphries
Journal of Cell Science 122, 4009–4011 (2009)
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Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6
JD Humphries*, A Byron*, MD Bass, SE Craig, JW Pinney, D Knight, MJ Humphries
Science Signaling 2, ra51 (2009)
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Giving off mixed signals — Distinct functions of α5β1 and αvβ3 integrins in regulating cell behaviour
MR Morgan, A Byron, MJ Humphries, MD Bass
IUBMB Life 61, 731–738 (2009)
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Mapping the ligand-binding pocket of integrin α5β1 using a gain-of-function approach
AP Mould, EJ Koper, A Byron, G Zahn, MJ Humphries
Biochemical Journal 424, 179–189 (2009)
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Integrin ligands at a glance
JD Humphries*, A Byron*, MJ Humphries
Journal of Cell Science 119, 3901–3903 (2006)
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Utilisation of the budding yeast Saccharomyces cerevisiae for the generation and isolation of non-lethal ricin A chain variants
SC Allen, A Byron, JM Lord, J Davey, LM Roberts, G Ladds
Yeast 22, 1287–1297 (2005)
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Book Sections

Characterization of the phospho-adhesome by mass spectrometry-based proteomics
J Robertson*, JD Humphries*, NR Paul, S Warwood, D Knight, A Byron, MJ Humphries
Methods in Molecular Biology 1636, 235–251 (2017)
PubMed

Clustering and network analysis of reverse phase protein array data
A Byron
Methods in Molecular Biology 1606, 171–191 (2017)
PubMed

Isolation of integrin-based adhesion complexes
MC Jones*, JD Humphries*, A Byron*, A Millon-Frémillon*, J Robertson*, NR Paul*, DHJ Ng*, JA Askari*, MJ Humphries*
Current Protocols in Cell Biology 66, 9.8.1–9.8.15 (2015)
PMCPubMed | Blog


Preprints

Improved LC-MS chromatographic alignment increases the accuracy of label-free quantitative proteomics: Comparison of spectral counting versus ion intensity-based proteomic quantification strategies
DHJ Ng, JD Humphries, JN Selley, S Warwood, D Knight, A Byron, MJ Humphries
bioRxiv, 111476 (2017)
PDF


Conference Proceedings

The role of Kindlin-1 in the initiation and progression of breast cancer
V Brunton, S Sarvi, M Muir, H Creedon, A Byron, H Patel
Breast Cancer Research and Treatment 159, 189 (2016)

Utilisation of reverse phase protein array analysis to identify signalling pathways activated in lobular breast cancer
K Teo, M Tenhagen, A Byron, P Derksen, V Brunton
European Journal of Cancer 57, S122 (2016)

Sharpin is a novel activator of the Arp2/3 complex
MH Khan, S Salomaa, A Augenlicht, T Deguchi, G Jacquemet, E Kremneva, A Byron, MJ Humphries, P Hänninen, P Lappalainen, J Pouwels
Molecular Biology of the Cell 26, 4523 (2016)

Development and characteristics of resistance to the HER family tyrosine kinase inhibitor AZD8931
VG Brunton, H Creedon, M Muir, T Klinowska, K McLeod, A Byron
European Journal of Cancer 50, 160 (2014)

Proteomic profiling of adhesion complex dynamics
D Ng, JD Humphries, A Byron, A Carisey, MJ Humphries
Molecular Biology of the Cell 23, 4663 (2012)

Proteomic analysis of integrin-associated complexes from multipotent and early differentiated mesenchymal stem cells
JN Ajeian, JD Humphries, A Byron, JA Askari, A Millon-Frémillon, SE Craig, MJ Humphries
Molecular Biology of the Cell 23, 4663 (2012)

Quantitative proteomic profiling of adhesion receptor signalling
A Byron
International Journal of Experimental Pathology 92, A2–A3 (2011)

Phosphotyrosine-based proteomics of Jurkat T-cells after TCR clustering reveals novel potential regulators of immunological synapse formation
AP Mould, A Byron, EJ Koper, MJ Humphries
Immunology 131, 162–163 (2010)

Proteomic analysis of the extracellular matrix components from an in vitro model of liver fibrosis
ST Rashid, JD Humphries, A Byron, JA Askari, MJ Humphries
International Journal of Experimental Pathology 91, A34 (2010)

Quantitative proteomic analysis of integrin adhesion complexes
A Byron, JD Humphries, SE Craig, D Knight, MJ Humphries
International Journal of Experimental Pathology 91, A9–A10 (2010)

Development of a proteomic technique to analyze integrin-associated complexes in human embryonic stem cells
JN Ajeian, JD Humphries, A Byron, JA Askari, SE Craig, SJ Kimber, MJ Humphries
International Journal of Experimental Pathology 91, A8 (2010)


Magazine Articles

Omics meets cell biology
A Byron
BSCB Newsletter Autumn, 17–18 (2009)
ISSUU


Thesis

Proteomic analyses of integrin-based adhesion complexes
A Byron
PhD thesis. University of Manchester (2008)


Metrics et cetera

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*These authors contributed equally to this work
**These authors contributed equally to this work
Corresponding author(s) (otherwise last author)


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