Our Primer on adhesion signalling complexes has been published in the current issue of Current Biology.
The article provides an accesible overview of the role of extracellular-matrix receptors and their associated protein complexes and signalling networks in the control of cell adhesion and migration. We focus on the molecular complexity of adhesion signalling complexes and mechanisms of their regulation, which impact on many aspects of cell behaviour in health and disease.
Citation: A Byron, MR Morgan, MJ Humphries, Adhesion signalling complexes. Curr. Biol. 20, R1063–R1067 (2010). DOI | PubMed
Adam Byron 
[…] position. Depending on the shape of the integrins, different proteins attach to them to assist in the signalling process. But which proteins bind to different conformations of integrins, and how […]
[…] of cell adhesion. These points of attachment contain hundreds of different proteins – so-called adhesion complexes – that act together to signal and control cell behaviour. Working out how phosphorylation plays […]
[…] proteins inside cells are recruited to adhesion receptors to form multi-protein assemblies called adhesion complexes. The networks of adhesion proteins and their interactions work to control the migration, […]