A press release has been issued by Cancer Research UK about a paper from the University of Edinburgh on the protein focal adhesion kinase (or FAK) and how it modulates the immune system in cancer to allow tumour cells to grow.
A class of experimental drug treatments already in clinical trials could also help the body’s immune system to fight cancer.
By blocking FAK from working, we could help the immune system to recognise and fight cancer.
The news is also reported by the University of Edinburgh here.
Funding
This work was supported by Cancer Research UK, the European Research Council and the Medical Research Council.
Citation
Serrels et al. Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity. Cell 163, 160–173 (2015)
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8 October 2015 //
Update
This work has been highlighted in the journal Cancer Discovery.
[…] regulatory T cells from the immune system. In skin cancer, this results in the cancer cells evading destruction by the immune system, which leads to tumour […]