Our paper has been published in this week’s issue of Science Signaling.

Our work describes a methodology for the isolation and proteomic analysis of ligand-induced integrin adhesion complexes. Using this approach, we identified regulator of chromosome condensation 2 (RCC2) as a component of fibronectin-activated integrin signalling pathways that regulate cell migration.

Science Signaling cover, 2009, vol. 2 (no. 87) // Image by Adam Byron // Reproduced with permission from AAAS

Science Signaling cover, 2009, vol. 2 (no. 87)

There is an associated research summary written by the editors of the journal.

The paper is featured on the cover of the journal using an image that I designed based on our data.

Citation: JD Humphries, A Byron, MD Bass, SE Craig, JW Pinney, D Knight, MJ Humphries, Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Sci. Signal. 2, ra51 (2009). DOI | PubMed

Advertisements