Archives for category: Research

Our recent Science Signaling Research Article is featured in Signaling Breakthroughs of the Year published in the current issue of Science Signaling.

The Signaling Breakthroughs of the Year Editorial Guide is an annual feature that shortlists the most important cell signalling advances of the previous year. Science Signaling Chief Scientific Editor Michael Yaffe (Massachusetts Institute of Technology, USA) highlighted our proteomic analysis of integrin signalling complexes as a notable contribution to the development of methodologies that enable network-level analyses of signal transduction, an important theme of this year’s selected signalling breakthroughs.

I am also pleased to have created one of the figures used in the Editorial Guide.

BSCB Newsletter cover, 2009, Autumn

BSCB Newsletter cover, 2009, Autumn

My Meeting Report on the Keystone Symposia meeting entitled “Omics Meets Cell Biology” has been published in the Autumn 2009 issue of the BSCB Newsletter.

I attended the Keystone Symposia on Molecular and Cellular Biology: Omics Meets Cell Biology meeting from 25–30 January 2009 in the snowy heights of Breckenridge, Colorado, USA. The conference, the first Omics Meets Cell Biology Keystone Symposium, brought together leading experts in cell biology and “omics” technologies (genomics, proteomics, metabolomics, etc.) to discuss the ever-growing interface between the two disciplines.
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I am pleased to have been invited to present a seminar at the Department of Biological Sciences, University of Warwick, UK. The seminar will cover my current work in the laboratory of Professor Martin Humphries (University of Manchester, UK), and it is titled “Analysing the complexity of cell adhesion: A proteomic approach.”

I completed my undergraduate degree at Warwick in 2004 so am really looking forward to seeing how the department has changed. Indeed, I was asked to present this seminar by Professor Lynne Roberts who was my supervisor for my final-year undergraduate research project.

The seminar is at 3pm tomorrow (27 November 2009) on Gibbet Hill campus and is part of the Genes & Development Research Interest Group seminar series.

Adhesion complex network

Adhesion complex network

Our recent Science Signaling Research Article is featured in the current Top 10 cell biology papers evaluated on Faculty of 1000 Biology.

The Top 10 are generated using papers added to Faculty of 1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor, which incorporates both the number of times a paper has been evaluated and the ratings it has received.

In addition to the evaluation by Herbert Schiller and Reinhard Fässler (Max Planck Gesellschaft, Germany), our article has now also been selected and evaluated by Alexey Belkin (University of Maryland, MD, USA).

Journal of Cell Science poster concept art

Journal of Cell Science poster concept art

Our review on anti-integrin antibodies has been published in today’s issue of Journal of Cell Science.

The Cell Science at a Glance article provides an overview of the mechanisms of antibody regulation of integrin adhesion receptors. The accompanying poster catalogues the best-characterised examples of function-regulating and non-functional antibodies. This review provides a resource for researchers to assess key reagents used in the study of integrin-mediated cell adhesion.

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