I attended the recent “Signaling by Adhesion Receptors” Gordon Research Conference (24-29 June) and associated Seminar (23-24 June) in Waterville, Maine, USA. The topics of both meetings covered research on signal transduction involving cell-cell and cell-extracellular matrix interactions. These interactions are essential for a multicellular existence. Unsurprisingly, when these processes go wrong, disease is often a consequence, and the implications of adhesion signalling in cancer were frequently discussed during the meetings.
Three of my images have been shortlisted for the European Proteomics Association (EuPA) 2012 Proteomics Photography and Graphic Arts Contest. The three images illustrate different aspects of proteomics, which is the study of all proteins in a given system, such as a cell. You can vote for your favourite image here.
I have recently returned from the Keystone Symposia meeting “Proteomics, Interactomes” that took place in Stockholm, Sweden (7th-12th May). It was the first Keystone Symposia meeting in Stockholm, which, although lacking the ski slopes so often sampled at Keystone meetings, made for a very pleasant venue. It was also the inaugural “Proteomics, Interactomes” conference, and hopefully it will be the first of many. The meeting was a great success, with an excellent range of speakers.
Work by Mark Bass and others has been published in this week’s issue of Developmental Cell.
This study investigates the cellular mechanisms that are required for tissue repair. To heal a wound, cells called fibroblasts must migrate through the surrounding extracellular matrix to the site of damage. Once at the damaged tissue, fibroblasts contract the wound and begin the healing process. This paper identifies how cells can detect and respond efficiently to tissue damage.
My photograph has been shortlisted for the University of Manchester Images of Research Photography Competition. My image analogises fishing to the molecular techniques I use in the laboratory to investigate cell adhesion.
The shortlisted images are currently being exhibited at the John Rylands Library, Deansgate (3-28 October), and then at the University of Manchester Science Spectacular event at Whitworth Hall (29 October). You can vote for your favourite image at one of these exhibitions or online here!





