Archives for category: Research

My paper has been published in the current issue of the journal Proteomics. The paper also makes the cover of the issue, which is a special issue on the theme of Cancer Proteomics.

Proteomics cover, 2012, vol. 12 (no. 13) // Images by Adam Byron & Sue Craig // Reproduced with permission from Wiley-VCH Verlag GmbH & Co. KGaA

Proteomics cover, 2012, vol. 12 (no. 13)

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I attended the recent “Signaling by Adhesion Receptors” Gordon Research Conference (24-29 June) and associated Seminar (23-24 June) in Waterville, Maine, USA. The topics of both meetings covered research on signal transduction involving cell-cell and cell-extracellular matrix interactions. These interactions are essential for a multicellular existence. Unsurprisingly, when these processes go wrong, disease is often a consequence, and the implications of adhesion signalling in cancer were frequently discussed during the meetings.

Maine Lobster // Image by Adam Byron

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I have recently returned from the Keystone Symposia meeting “Proteomics, Interactomes” that took place in Stockholm, Sweden (7th-12th May). It was the first Keystone Symposia meeting in Stockholm, which, although lacking the ski slopes so often sampled at Keystone meetings, made for a very pleasant venue. It was also the inaugural “Proteomics, Interactomes” conference, and hopefully it will be the first of many. The meeting was a great success, with an excellent range of speakers.

View of Östermalm from Djurgårdsbron // Image by Adam Byron

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Work by Mark Bass and others has been published in this week’s issue of Developmental Cell.

This study investigates the cellular mechanisms that are required for tissue repair. To heal a wound, cells called fibroblasts must migrate through the surrounding extracellular matrix to the site of damage. Once at the damaged tissue, fibroblasts contract the wound and begin the healing process. This paper identifies how cells can detect and respond efficiently to tissue damage.

Molecules required for wound healing // Image by Adam Byron

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I will be in Dublin, Ireland, for the upcoming EMBO Cancer Proteomics meeting (20th-23rd June). I am pleased to have been selected to present a talk at the conference. My presentation will describe my current work in the lab of Professor Martin Humphries (University of Manchester, UK) on the proteomic analysis of integrin adhesion signalling in cancer cells, with a focus on the integrative analysis of these complex data.

The meeting, entitled “Systems Biology, Developmental Models & Data Integration,” is the second event in the EMBO Conference Series on Cancer Proteomics. The focus of the 2011 meeting is on using proteomic approaches to delineate mechanisms of cancer biology. It promises to be a very interesting meeting, and the programme looks really good!